The dermis layer is composed mainly of fibroblasts and the intracellular matrix, where collagen, elastin and glycosaminoglycans are found, as is hyaluronic acid. Hyaluronic acid is particularly important for skin moisture and the active activity of fibroblasts. Fibroblasts synthesize collagen, which is required as a skin support structure. Skin aging reduces the amount of hyaluronic acid in the dermis and reduces its synthesis. This results in a decrease in elasticity and firmness of the skin as well as dehydration and wrinkle formation. F-HA and F-HA + are low molecular weight hyaluronic acid and have the same molecular size as hyaluronic acid in the skin. This specific size of molecules allows the substance to penetrate the skin and act not only on the epidermis but also on the dermis, where skin moisture is regulated and skin firmness is increased.